SDK1
Summary: The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains six immunoglobulin-like domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:607216 Ensembl IDEnsembl:ENSG00000146555 HGNC IDHGNC:HGNC:19307 PHARMGKB IDPA134957188 Map Location7p22.2 | |||||
GO terms in SDK1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | ISS | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules |
| BP | ISS | GO:0007416 | synapse assembly |
| BP | ISS | GO:0010842 | retina layer formation |
| BP | TAS | GO:0045216 | cell-cell junction organization |
| BP | IEA | GO:0048148 | behavioral response to cocaine |
| BP | IEA | GO:0060998 | regulation of dendritic spine development |
Gene expression in normal tissue: SDK1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SDK1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1500931 | Cell-Cell communication |
| reactome | R-HSA-373756 | SDK interactions |
| reactome | R-HSA-421270 | Cell-cell junction organization |
| reactome | R-HSA-446728 | Cell junction organization |
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Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SDK1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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