FGF14
Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:601515 Ensembl IDEnsembl:ENSG00000102466 HGNC IDHGNC:HGNC:3671 PHARMGKB IDPA28110 Map Location13q33.1 |
GO terms in FGF14
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
BP | TAS | GO:0007165 | signal transduction |
BP | TAS | GO:0007267 | cell-cell signaling |
BP | IEA | GO:0007399 | nervous system development |
BP | IEA | GO:0010469 | regulation of signaling receptor activity |
BP | IEA | GO:0048167 | regulation of synaptic plasticity |
BP | IEA | GO:0060078 | regulation of postsynaptic membrane potential |
Gene expression in normal tissue: FGF14
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in FGF14
Loading, please wait...
Database | Pathway ID | Pathway Des. |
---|---|---|
wikipathways | WP382 | MAPK Signaling Pathway |
wikipathways | WP3931 | ESC Pluripotency Pathways |
wikipathways | WP3932 | Focal Adhesion-PI3K-Akt-mTOR-signaling pathway |
wikipathways | WP4172 | PI3K-Akt Signaling Pathway |
wikipathways | WP51 | Regulation of Actin Cytoskeleton |
reactome | R-HSA-397014 | Muscle contraction |
Gene-Drug: Aster Plot
Loading, please wait...
Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD309 | 17AAG | 1 |
Showing 1 to 1 of 1 rows
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in FGF14
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
---|---|---|---|---|---|---|---|---|
No matching records found |