SEPHS1

Summary: This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. [provided by RefSeq, Sep 2010].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameselenophosphate synthetase 1
OMIM IDMIM:600902
Ensembl IDEnsembl:ENSG00000086475
HGNC IDHGNC:HGNC:19685
PHARMGKB IDPA134905215
Map Location10p13

Gene Categories:

KINASE

GO terms in SEPHS1


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IBA GO:0001887 selenium compound metabolic process
BP TAS GO:0006464 cellular protein modification process
BP IBA GO:0016260 selenocysteine biosynthetic process
BP IEA GO:0016260 selenocysteine biosynthetic process
BP IEA GO:0016310 phosphorylation
BP IBA GO:0070329 tRNA seleno-modification
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Gene expression in normal tissue: SEPHS1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SEPHS1


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Database
Pathway ID
Pathway Des.
kegg hsa00450 Selenocompound metabolism - Homo sapiens (human)
humancyc PWY-6281 selenocysteine biosynthesis
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SEPHS1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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