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POGZ

Summary: The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Aug 2010].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
pogo transposable element derived with ZNF domain	MIM:614787	Ensembl:ENSG00000143442	HGNC:HGNC:18801	PA38685	1q21.3

GO terms in POGZ

Term Type	Evidence Type	GO Term ID	GO Des.
MF	ISA	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF	IEA	GO:0003677	DNA binding
MF	IPI	GO:0005515	protein binding
MF	IEA	GO:0046872	metal ion binding
CC	IDA	GO:0000790	nuclear chromatin
CC	IBA	GO:0005634	nucleus
CC	IDA	GO:0005634	nucleus
CC	IDA	GO:0005654	nucleoplasm
CC	IDA	GO:0005737	cytoplasm
CC	IDA	GO:0005829	cytosol
CC	IBA	GO:0035097	histone methyltransferase complex
BP	IEA	GO:0006357	regulation of transcription by RNA polymerase II
BP	IMP	GO:0007064	mitotic sister chromatid cohesion
BP	IBA	GO:0010468	regulation of gene expression
BP	IBA	GO:0016569	covalent chromatin modification
BP	IBA	GO:0031060	regulation of histone methylation
BP	IEA	GO:0051301	cell division
BP	IMP	GO:0051382	kinetochore assembly

Gene expression in normal tissue: POGZ

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in POGZ

Database	Pathway ID	Pathway Des.

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD353	PD0325901	1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in POGZ

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DATATYPES

CLASSFICATION

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