ADGRL2
Summary: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors. The encoded protein participates in the regulation of exocytosis. The proprotein is thought to be further cleaved within a cysteine-rich G-protein-coupled receptor proteolysis site into two chains that are non-covalently bound at the cell membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:607018 Ensembl IDEnsembl:ENSG00000117114 HGNC IDHGNC:HGNC:18582 PHARMGKB IDPA38589 Map Location1p31.1 | |||||
GO terms in ADGRL2
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0007166 | cell surface receptor signaling pathway |
| BP | NAS | GO:0007186 | G-protein coupled receptor signaling pathway |
| BP | IBA | GO:0007420 | brain development |
| CC | IBA | GO:0005887 | integral component of plasma membrane |
| CC | NAS | GO:0016021 | integral component of membrane |
| CC | IBA | GO:0043005 | neuron projection |
Gene expression in normal tissue: ADGRL2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ADGRL2
Gene-Drug: Aster Plot
Loading, please wait...
Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD97 | Bexarotene | 1 |
Showing 1 to 1 of 1 rows
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ADGRL2
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.