CLEC16A
Summary: This gene encodes a member of the C-type lectin domain containing family. Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| C-type lectin domain containing 16A | MIM:611303 | Ensembl:ENSG00000038532 | HGNC:HGNC:29013 | PA162382340 | 16p13.13 |
GO terms in CLEC16A
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ND | GO:0003674 | molecular_function |
| MF | IBA | GO:0017137 | Rab GTPase binding |
| CC | IBA | GO:0005770 | late endosome |
| CC | IDA | GO:0005794 | Golgi apparatus |
| CC | IDA | GO:0005829 | cytosol |
| CC | IBA | GO:0016021 | integral component of membrane |
| CC | IDA | GO:0031982 | vesicle |
| CC | IBA | GO:0036020 | endolysosome membrane |
| CC | IEA | GO:0036020 | endolysosome membrane |
| BP | IEA | GO:0006914 | autophagy |
| BP | IBA | GO:0008333 | endosome to lysosome transport |
| BP | IMP | GO:0009267 | cellular response to starvation |
| BP | IBA | GO:0016197 | endosomal transport |
| BP | IEA | GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process |
| BP | IBA | GO:1901096 | regulation of autophagosome maturation |
| BP | IMP | GO:1901097 | negative regulation of autophagosome maturation |
| BP | IEA | GO:1901098 | positive regulation of autophagosome maturation |
| BP | IEA | GO:1901525 | negative regulation of mitophagy |
| BP | IMP | GO:1904263 | positive regulation of TORC1 signaling |
| BP | IMP | GO:1904766 | negative regulation of macroautophagy by TORC1 signaling |
Gene expression in normal tissue: CLEC16A
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CLEC16A
CLASSFICATION
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