SSBP2

Summary: This gene encodes a subunit of a protein complex that interacts with single-stranded DNA and is involved in the DNA damage response and maintenance of genome stability. The encoded protein may also play a role in telomere repair. A variant of this gene may be associated with survival in human glioblastoma patients. [provided by RefSeq, Sep 2016].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namesingle stranded DNA binding protein 2
OMIM IDMIM:607389
Ensembl IDEnsembl:ENSG00000145687
HGNC IDHGNC:HGNC:15831
PHARMGKB IDPA38046
Map Location5q14.1

GO terms in SSBP2


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding
MF IBA GO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
MF NAS GO:0003697 single-stranded DNA binding
MF IPI GO:0005515 protein binding
BP NAS GO:0006355 regulation of transcription, DNA-templated
BP IEA GO:0006366 transcription by RNA polymerase II
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Gene expression in normal tissue: SSBP2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SSBP2


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SSBP2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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