CADM1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| cell adhesion molecule 1 | MIM:605686 | Ensembl:ENSG00000182985 | HGNC:HGNC:5951 | PA29764 | 11q23.3 |
GO terms in CADM1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IDA | GO:0005886 | plasma membrane |
| CC | TAS | GO:0005886 | plasma membrane |
| CC | ISS | GO:0005911 | cell-cell junction |
| CC | ISS | GO:0016323 | basolateral plasma membrane |
| CC | IEA | GO:0045202 | synapse |
| BP | IDA | GO:0001913 | T cell mediated cytotoxicity |
| BP | IEA | GO:0006915 | apoptotic process |
| BP | ISS | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules |
| BP | ISS | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules |
| BP | IEA | GO:0007275 | multicellular organism development |
| BP | IEA | GO:0007283 | spermatogenesis |
| BP | IDA | GO:0008037 | cell recognition |
| BP | ISS | GO:0008037 | cell recognition |
| BP | IEA | GO:0030154 | cell differentiation |
| BP | TAS | GO:0034332 | adherens junction organization |
| BP | IBA | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity |
| BP | IDA | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity |
| BP | ISS | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity |
| BP | IDA | GO:0045954 | positive regulation of natural killer cell mediated cytotoxicity |
| BP | ISS | GO:0045954 | positive regulation of natural killer cell mediated cytotoxicity |
| BP | IDA | GO:0050715 | positive regulation of cytokine secretion |
| BP | IDA | GO:0050798 | activated T cell proliferation |
| BP | IDA | GO:0051606 | detection of stimulus |
| BP | ISS | GO:0051606 | detection of stimulus |
| MF | IPI | GO:0005102 | signaling receptor binding |
| MF | ISS | GO:0005102 | signaling receptor binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | ISS | GO:0030165 | PDZ domain binding |
| MF | ISS | GO:0042803 | protein homodimerization activity |
Gene expression in normal tissue: CADM1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CADM1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa04514 | Cell adhesion molecules (CAMs) - Homo sapiens (human) |
| wikipathways | WP4148 | Splicing factor NOVA regulated synaptic proteins |
| reactome | R-HSA-1500931 | Cell-Cell communication |
| reactome | R-HSA-418990 | Adherens junctions interactions |
| reactome | R-HSA-420597 | Nectin/Necl trans heterodimerization |
| reactome | R-HSA-421270 | Cell-cell junction organization |
| reactome | R-HSA-446728 | Cell junction organization |
| biocarta | rac1pathway | rac1 cell motility signaling pathway |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
| iGMDRD68 | Paclitaxel | 1 |
| iGMDRD309 | 17AAG | 1 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CADM1
CLASSFICATION
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