MCM9

Summary: The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1. [provided by RefSeq, Nov 2010].

Loading, please wait...
Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameminichromosome maintenance 9 homologous recombination repair factor
OMIM IDMIM:610098
Ensembl IDEnsembl:ENSG00000111877
HGNC IDHGNC:HGNC:21484
PHARMGKB IDPA162395071
Map Location6q22.31

Gene Categories:

DNA REPAIR

GO terms in MCM9


Loading, please wait...
Term Type
Evidence Type
GO Term ID
GO Des.
CC IEA GO:0005634 nucleus
CC IDA GO:0097362 MCM8-MCM9 complex
BP IDA GO:0000724 double-strand break repair via homologous recombination
BP IEA GO:0006270 DNA replication initiation
BP IDA GO:0006974 cellular response to DNA damage stimulus
BP ISS GO:0007292 female gamete generation
Showing 1 to 6 of 9 rows

Gene expression in normal tissue: MCM9

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

Pathways in MCM9


Loading, please wait...
Database
Pathway ID
Pathway Des.
wikipathways WP179 Cell Cycle
Showing 1 to 1 of 1 rows

Gene-Drug: Aster Plot


Loading, please wait...
Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 1
Showing 1 to 1 of 1 rows

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MCM9

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.