SHPRH

Summary: SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).[supplied by OMIM, Mar 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameSNF2 histone linker PHD RING helicase
OMIM IDMIM:608048
Ensembl IDEnsembl:ENSG00000146414
HGNC IDHGNC:HGNC:19336
PHARMGKB IDPA134880315
Map Location6q24.3

Gene Categories:

DNA REPAIR

GO terms in SHPRH


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IEA GO:0003677 DNA binding
MF IEA GO:0004386 helicase activity
MF IDA GO:0004842 ubiquitin-protein transferase activity
MF IPI GO:0005515 protein binding
MF IEA GO:0005524 ATP binding
MF IDA GO:0031625 ubiquitin protein ligase binding
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Gene expression in normal tissue: SHPRH

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SHPRH


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Database
Pathway ID
Pathway Des.
reactome R-HSA-392499 Metabolism of proteins
reactome R-HSA-597592 Post-translational protein modification
reactome R-HSA-8852135 Protein ubiquitination
reactome R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SHPRH

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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