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RAB26

Summary: Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling (summary by Seki et al., 2000 [PubMed 11043516]).[supplied by OMIM, Nov 2010].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
RAB26, member RAS oncogene family	MIM:605455	Ensembl:ENSG00000167964	HGNC:HGNC:14259	PA34116	16p13.3

GO terms in RAB26

Term Type	Evidence Type	GO Term ID	GO Des.
CC	IDA	GO:0000139	Golgi membrane
CC	IBA	GO:0012505	endomembrane system
CC	IEA	GO:0030658	transport vesicle membrane
CC	ISS	GO:0030667	secretory granule membrane
CC	ISS	GO:0031226	intrinsic component of plasma membrane
BP	IBA	GO:0006886	intracellular protein transport
BP	ISS	GO:0017157	regulation of exocytosis
BP	IBA	GO:0032482	Rab protein signal transduction
BP	IMP	GO:0035272	exocrine system development
BP	ISS	GO:0035272	exocrine system development
BP	IMP	GO:0043001	Golgi to plasma membrane protein transport
BP	IMP	GO:0045055	regulated exocytosis
MF	IBA	GO:0003924	GTPase activity
MF	IEA	GO:0003924	GTPase activity
MF	IPI	GO:0005515	protein binding
MF	IMP	GO:0005525	GTP binding
MF	ISS	GO:0005525	GTP binding
MF	IMP	GO:0019002	GMP binding

Gene expression in normal tissue: RAB26

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in RAB26

Database	Pathway ID	Pathway Des.
reactome	R-HSA-392499	Metabolism of proteins
reactome	R-HSA-597592	Post-translational protein modification
reactome	R-HSA-8873719	RAB geranylgeranylation

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD309	17AAG	1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RAB26

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