USP49
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| ubiquitin specific peptidase 49 | Ensembl:ENSG00000164663 | HGNC:HGNC:20078 | PA134954570 | 6p21.1 |
GO terms in USP49
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IMP | GO:0000398 | mRNA splicing, via spliceosome |
| BP | IEA | GO:0006511 | ubiquitin-dependent protein catabolic process |
| BP | IDA | GO:0016579 | protein deubiquitination |
| BP | TAS | GO:0016579 | protein deubiquitination |
| BP | IDA | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination |
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | IBA | GO:0005737 | cytoplasm |
| MF | IMP | GO:0004197 | cysteine-type endopeptidase activity |
| MF | IDA | GO:0004843 | thiol-dependent ubiquitin-specific protease activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0008270 | zinc ion binding |
| MF | IDA | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity |
| MF | TAS | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity |
| MF | IDA | GO:0042393 | histone binding |
Gene expression in normal tissue: USP49
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in USP49
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-5688426 | Deubiquitination |
| reactome | R-HSA-5689880 | Ub-specific processing proteases |
| reactome | R-HSA-597592 | Post-translational protein modification |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in USP49
CLASSFICATION
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