TOR1AIP1
Summary: This gene encodes a type 2 integral membrane protein that binds A- and B-type lamins. The encoded protein localizes to the inner nuclear membrane and may be involved in maintaining the attachment of the nuclear membrane to the nuclear lamina during cell division. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2016].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:614512 Ensembl IDEnsembl:ENSG00000143337 HGNC IDHGNC:HGNC:29456 PHARMGKB IDPA142670715 Map Location1q25.2 | |||||
GO terms in TOR1AIP1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IDA | GO:0032781 | positive regulation of ATPase activity |
| BP | ISS | GO:0034504 | protein localization to nucleus |
| BP | IEA | GO:0071763 | nuclear membrane organization |
| CC | IDA | GO:0005634 | nucleus |
| CC | IEA | GO:0005637 | nuclear inner membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
Gene expression in normal tissue: TOR1AIP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TOR1AIP1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TOR1AIP1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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