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GBGT1

Summary: This gene encodes a glycosyltransferase that plays a role in the synthesis of Forssman glycolipid (FG), a member of the globoseries glycolipid family. Glycolipids such as FG form attachment sites for the binding of pathogens to cells; expression of this protein may determine host tropism to microorganisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013].

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Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
Namegloboside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group) OMIM IDMIM:606074 Ensembl IDEnsembl:ENSG00000148288 HGNC IDHGNC:HGNC:20460 PHARMGKB IDPA134967297 Map Location9q34.2

GO terms in GBGT1

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Term Type	Evidence Type	GO Term ID	GO Des.
BP	IEA	GO:0005975	carbohydrate metabolic process
BP	IEA	GO:0006486	protein glycosylation
BP	TAS	GO:0009247	glycolipid biosynthetic process
BP	IBA	GO:0030259	lipid glycosylation
CC	IEA	GO:0000139	Golgi membrane
CC	IBA	GO:0005794	Golgi apparatus

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Gene expression in normal tissue: GBGT1

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in GBGT1

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Database	Pathway ID	Pathway Des.
kegg	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series - Homo sapiens (human)

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Gene-Drug: Aster Plot

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Drug ID	Drug Name	Model Num.
iGMDRD353	PD0325901	1

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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in GBGT1

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	Model	Level	Reference ID	Tissue	Cancer	Drug	Clinical Response	Source
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