STEAP1
Summary: This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:604415 Ensembl IDEnsembl:ENSG00000164647 HGNC IDHGNC:HGNC:11378 PHARMGKB IDPA36193 Map Location7q21.13 | |||||
GO terms in STEAP1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0015677 | copper ion import |
| BP | IEA | GO:0055072 | iron ion homeostasis |
| BP | IBA | GO:0055114 | oxidation-reduction process |
| BP | IEA | GO:0055114 | oxidation-reduction process |
| BP | IBA | GO:0098706 | ferric iron import across plasma membrane |
| CC | IBA | GO:0005768 | endosome |
Gene expression in normal tissue: STEAP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in STEAP1
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 2 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in STEAP1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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