PCDH17
Summary: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein contains six extracellular cadherin domains, a transmembrane domain, and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein may play a role in the establishment and function of specific cell-cell connections in the brain. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| protocadherin 17 | MIM:611760 | Ensembl:ENSG00000118946 | HGNC:HGNC:14267 | PA33001 | 13q21.1 |
GO terms in PCDH17
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0005509 | calcium ion binding |
| MF | IPI | GO:0005515 | protein binding |
| BP | IBA | GO:0007155 | cell adhesion |
| BP | IEA | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules |
| BP | IBA | GO:0007267 | cell-cell signaling |
| BP | IEA | GO:0030534 | adult behavior |
| BP | IEA | GO:0050805 | negative regulation of synaptic transmission |
| BP | IEA | GO:1904071 | presynaptic active zone assembly |
| BP | IEA | GO:2000807 | regulation of synaptic vesicle clustering |
| CC | IBA | GO:0005887 | integral component of plasma membrane |
Gene expression in normal tissue: PCDH17
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PCDH17
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PCDH17
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.