GNAZ

Summary: The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameG protein subunit alpha z
OMIM IDMIM:139160
Ensembl IDEnsembl:ENSG00000128266
HGNC IDHGNC:HGNC:4395
PHARMGKB IDPA28775
Map Location22q11.22-q11.23

GO terms in GNAZ


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0001664 G-protein coupled receptor binding
MF IBA GO:0003924 GTPase activity
MF TAS GO:0003924 GTPase activity
MF IPI GO:0005515 protein binding
MF TAS GO:0005525 GTP binding
MF IBA GO:0031683 G-protein beta/gamma-subunit complex binding
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Gene expression in normal tissue: GNAZ

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Gene-drug pathway distribution

Pathways in GNAZ


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Database
Pathway ID
Pathway Des.
reactome R-HSA-111885 Opioid Signalling
reactome R-HSA-111885 Opioid Signalling
reactome R-HSA-112040 G-protein mediated events
reactome R-HSA-112040 G-protein mediated events
reactome R-HSA-112043 PLC beta mediated events
reactome R-HSA-112043 PLC beta mediated events
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in GNAZ

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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