GNGT2
Summary: Phototransduction in rod and cone photoreceptors is regulated by groups of signaling proteins. The encoded protein is thought to play a crucial role in cone phototransduction. It belongs to the G protein gamma family and localized specifically in cones. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2010].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:139391 Ensembl IDEnsembl:ENSG00000167083 HGNC IDHGNC:HGNC:4412 PHARMGKB IDPA28791 Map Location17q21.32 |
GO terms in GNGT2
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IBA | GO:0003924 | GTPase activity |
MF | IDA | GO:0003924 | GTPase activity |
MF | NAS | GO:0003924 | GTPase activity |
BP | NAS | GO:0007186 | G-protein coupled receptor signaling pathway |
BP | NAS | GO:0007602 | phototransduction |
CC | IBA | GO:0005834 | heterotrimeric G-protein complex |
Gene expression in normal tissue: GNGT2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GNGT2
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Database | Pathway ID | Pathway Des. |
---|---|---|
biocarta | rhodopsinpathway | visual signal transduction |
reactome | R-HSA-109582 | Hemostasis |
reactome | R-HSA-109582 | Hemostasis |
reactome | R-HSA-111885 | Opioid Signalling |
reactome | R-HSA-112314 | Neurotransmitter receptors and postsynaptic signal transmission |
reactome | R-HSA-112315 | Transmission across Chemical Synapses |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in GNGT2
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |