PRLHR
Summary: PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002 [PubMed 11923475]).[supplied by OMIM, Mar 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| prolactin releasing hormone receptor | MIM:600895 | Ensembl:ENSG00000119973 | HGNC:HGNC:4464 | PA28847 | 10q26.11 |
GO terms in PRLHR
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | TAS | GO:0005886 | plasma membrane |
| CC | TAS | GO:0005887 | integral component of plasma membrane |
| BP | TAS | GO:0007186 | G-protein coupled receptor signaling pathway |
| BP | IEA | GO:0007218 | neuropeptide signaling pathway |
| BP | TAS | GO:0007565 | female pregnancy |
| BP | IEA | GO:0042445 | hormone metabolic process |
| MF | TAS | GO:0004930 | G-protein coupled receptor activity |
| MF | IEA | GO:0004983 | neuropeptide Y receptor activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | TAS | GO:0008188 | neuropeptide receptor activity |
Gene expression in normal tissue: PRLHR
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PRLHR
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa04080 | Neuroactive ligand-receptor interaction - Homo sapiens (human) |
| wikipathways | WP455 | GPCRs, Class A Rhodopsin-like |
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-372790 | Signaling by GPCR |
| reactome | R-HSA-373076 | Class A/1 (Rhodopsin-like receptors) |
| reactome | R-HSA-375276 | Peptide ligand-binding receptors |
| reactome | R-HSA-500792 | GPCR ligand binding |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PRLHR
CLASSFICATION
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