GRID1
Summary: This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:610659 Ensembl IDEnsembl:ENSG00000182771 HGNC IDHGNC:HGNC:4575 PHARMGKB IDPA28970 Map Location10q23.1-q23.2 | |||||
GO terms in GRID1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0004970 | ionotropic glutamate receptor activity |
| MF | IEA | GO:0005234 | extracellularly glutamate-gated ion channel activity |
| MF | IBA | GO:0008066 | glutamate receptor activity |
| MF | IBA | GO:1904315 | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential |
| BP | IEA | GO:0034220 | ion transmembrane transport |
| BP | ISS | GO:0035176 | social behavior |
Gene expression in normal tissue: GRID1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GRID1
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD68 | Paclitaxel | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GRID1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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