GRID1
Summary: This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| glutamate ionotropic receptor delta type subunit 1 | MIM:610659 | Ensembl:ENSG00000182771 | HGNC:HGNC:4575 | PA28970 | 10q23.1-q23.2 |
GO terms in GRID1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0004970 | ionotropic glutamate receptor activity |
| MF | IEA | GO:0005234 | extracellularly glutamate-gated ion channel activity |
| MF | IBA | GO:0008066 | glutamate receptor activity |
| MF | IBA | GO:1904315 | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential |
| BP | IEA | GO:0034220 | ion transmembrane transport |
| BP | ISS | GO:0035176 | social behavior |
| BP | IEA | GO:0035235 | ionotropic glutamate receptor signaling pathway |
| BP | IBA | GO:0035249 | synaptic transmission, glutamatergic |
| BP | IBA | GO:0050804 | modulation of chemical synaptic transmission |
| BP | IEA | GO:0060079 | excitatory postsynaptic potential |
| CC | IBA | GO:0005886 | plasma membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| CC | IEA | GO:0030054 | cell junction |
| CC | IBA | GO:0045211 | postsynaptic membrane |
| CC | IEA | GO:0045211 | postsynaptic membrane |
| CC | HDA | GO:0070062 | extracellular exosome |
| CC | IBA | GO:0098839 | postsynaptic density membrane |
Gene expression in normal tissue: GRID1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GRID1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa04080 | Neuroactive ligand-receptor interaction - Homo sapiens (human) |
| wikipathways | WP3584 | MECP2 and Associated Rett Syndrome |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GRID1
CLASSFICATION
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