NTMT1
Summary: The METTL11A gene encodes an N-terminal methyltransferase for the RAN (MIM 601179) guanine nucleotide exchange factor regulator of chromosome condensation 1 (RCC1; MIM 179710). METTL11A enzyme alpha-N-methylates other protein targets such as SET (MIM 600960) and RB (MIM 180200).[supplied by OMIM, Nov 2010].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:613560 Ensembl IDEnsembl:ENSG00000148335 HGNC IDHGNC:HGNC:23373 PHARMGKB IDPA162395788 Map Location9q34.11 | |||||
Gene Categories:
HISTONE MODIFICATIONGO terms in NTMT1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| MF | IBA | GO:0008168 | methyltransferase activity |
| MF | IDA | GO:0008276 | protein methyltransferase activity |
| MF | IDA | GO:0042054 | histone methyltransferase activity |
| MF | IBA | GO:0071885 | N-terminal protein N-methyltransferase activity |
| MF | IDA | GO:0071885 | N-terminal protein N-methyltransferase activity |
Gene expression in normal tissue: NTMT1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in NTMT1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD309 | 17AAG | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in NTMT1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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