PACSIN3

Summary: This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameprotein kinase C and casein kinase substrate in neurons 3
OMIM IDMIM:606513
Ensembl IDEnsembl:ENSG00000165912
HGNC IDHGNC:HGNC:8572
PHARMGKB IDPA32898
Map Location11p11.2

Gene Categories:

ION CHANNELTRANSPORTER

GO terms in PACSIN3


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IEA GO:0006897 endocytosis
BP IBA GO:0007010 cytoskeleton organization
BP IBA GO:0030100 regulation of endocytosis
BP ISS GO:0045806 negative regulation of endocytosis
BP IMP GO:0051044 positive regulation of membrane protein ectodomain proteolysis
BP ISS GO:0051926 negative regulation of calcium ion transport
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Gene expression in normal tissue: PACSIN3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PACSIN3


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Database
Pathway ID
Pathway Des.
reactome R-HSA-199991 Membrane Trafficking
reactome R-HSA-5653656 Vesicle-mediated transport
reactome R-HSA-8856828 Clathrin-mediated endocytosis
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PACSIN3

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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