PACSIN1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| protein kinase C and casein kinase substrate in neurons 1 | MIM:606512 | Ensembl:ENSG00000124507 | HGNC:HGNC:8570 | PA32896 | 6p21.31 |
GO terms in PACSIN1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| MF | IBA | GO:0005543 | phospholipid binding |
| MF | IDA | GO:0005543 | phospholipid binding |
| MF | IBA | GO:0008092 | cytoskeletal protein binding |
| MF | IEA | GO:0008092 | cytoskeletal protein binding |
| MF | IEA | GO:0042802 | identical protein binding |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | IBA | GO:0005768 | endosome |
| CC | IEA | GO:0005829 | cytosol |
| CC | IBA | GO:0005856 | cytoskeleton |
| CC | IBA | GO:0005886 | plasma membrane |
| CC | ISS | GO:0005886 | plasma membrane |
| CC | IEA | GO:0030054 | cell junction |
| CC | IEA | GO:0030137 | COPI-coated vesicle |
| CC | IEA | GO:0030659 | cytoplasmic vesicle membrane |
| CC | ISS | GO:0032587 | ruffle membrane |
| CC | IEA | GO:0043209 | myelin sheath |
| CC | ISS | GO:0043679 | axon terminus |
| CC | ISS | GO:0045202 | synapse |
| CC | ISS | GO:0048471 | perinuclear region of cytoplasm |
| BP | IBA | GO:0007010 | cytoskeleton organization |
| BP | IEA | GO:0007015 | actin filament organization |
| BP | IBA | GO:0030100 | regulation of endocytosis |
| BP | IBA | GO:0030182 | neuron differentiation |
| BP | IEA | GO:0045806 | negative regulation of endocytosis |
| BP | ISS | GO:0048488 | synaptic vesicle endocytosis |
| BP | IBA | GO:0048812 | neuron projection morphogenesis |
| BP | ISS | GO:0048812 | neuron projection morphogenesis |
| BP | ISS | GO:0072657 | protein localization to membrane |
| BP | ISS | GO:0072659 | protein localization to plasma membrane |
| BP | IBA | GO:0097320 | plasma membrane tubulation |
| BP | IDA | GO:0097320 | plasma membrane tubulation |
| BP | IBA | GO:1900006 | positive regulation of dendrite development |
| BP | ISS | GO:1900006 | positive regulation of dendrite development |
Gene expression in normal tissue: PACSIN1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PACSIN1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-199991 | Membrane Trafficking |
| reactome | R-HSA-5653656 | Vesicle-mediated transport |
| reactome | R-HSA-8856828 | Clathrin-mediated endocytosis |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PACSIN1
CLASSFICATION
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