ZNRD1

Summary: This gene encodes a DNA-directed RNA polymerase I subunit. The encoded protein contains two potential zinc-binding motifs and may play a role in regulation of cell proliferation. The encoded protein may be involved in cancer and human immunodeficiency virus progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namezinc ribbon domain containing 1
OMIM IDMIM:607525
Ensembl IDEnsembl:ENSG00000066379
HGNC IDHGNC:HGNC:13182
PHARMGKB IDPA37754
Map Location6p22.1

GO terms in ZNRD1


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IBA GO:0000428 DNA-directed RNA polymerase complex
CC TAS GO:0005654 nucleoplasm
CC IBA GO:0005736 DNA-directed RNA polymerase I complex
BP TAS GO:0006139 nucleobase-containing compound metabolic process
BP TAS GO:0006361 transcription initiation from RNA polymerase I promoter
BP IBA GO:0006363 termination of RNA polymerase I transcription
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Gene expression in normal tissue: ZNRD1

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

Metabolic pathways1

Pathways in ZNRD1


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Database
Pathway ID
Pathway Des.
reactome R-HSA-212165 Epigenetic regulation of gene expression
reactome R-HSA-212165 Epigenetic regulation of gene expression
reactome R-HSA-427413 NoRC negatively regulates rRNA expression
reactome R-HSA-5250913 Positive epigenetic regulation of rRNA expression
reactome R-HSA-5250924 B-WICH complex positively regulates rRNA expression
reactome R-HSA-5250941 Negative epigenetic regulation of rRNA expression
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD68 Paclitaxel 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ZNRD1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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