DNAJB2
Summary: This gene is almost exclusively expressed in the brain, mainly in the neuronal layers. It encodes a protein that shows sequence similarity to bacterial DnaJ protein and the yeast homologs. In bacteria, this protein is implicated in protein folding and protein complex dissociation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:604139 Ensembl IDEnsembl:ENSG00000135924 HGNC IDHGNC:HGNC:5228 PHARMGKB IDPA27415 Map Location2q35 |
GO terms in DNAJB2
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IBA | GO:0001671 | ATPase activator activity |
MF | IDA | GO:0001671 | ATPase activator activity |
MF | IPI | GO:0005515 | protein binding |
MF | IBA | GO:0030544 | Hsp70 protein binding |
MF | IPI | GO:0030544 | Hsp70 protein binding |
MF | IDA | GO:0043130 | ubiquitin binding |
Gene expression in normal tissue: DNAJB2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in DNAJB2
Loading, please wait...
Database | Pathway ID | Pathway Des. |
---|---|---|
kegg | hsa04141 | Protein processing in endoplasmic reticulum - Homo sapiens (human) |
Showing 1 to 1 of 1 rows
Gene-Drug: Aster Plot
Loading, please wait...
Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD68 | Paclitaxel | 1 |
Showing 1 to 1 of 1 rows
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in DNAJB2
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
---|---|---|---|---|---|---|---|---|
No matching records found |