DNAJB2


Summary: This gene is almost exclusively expressed in the brain, mainly in the neuronal layers. It encodes a protein that shows sequence similarity to bacterial DnaJ protein and the yeast homologs. In bacteria, this protein is implicated in protein folding and protein complex dissociation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011].

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GO terms in DNAJB2


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0001671 ATPase activator activity
MF IDA GO:0001671 ATPase activator activity
MF IPI GO:0005515 protein binding
MF IBA GO:0030544 Hsp70 protein binding
MF IPI GO:0030544 Hsp70 protein binding
MF IDA GO:0043130 ubiquitin binding
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Gene expression in normal tissue: DNAJB2

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

Metabolic pathways1

Pathways in DNAJB2


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Database
Pathway ID
Pathway Des.
kegg hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD68 Paclitaxel 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in DNAJB2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
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