IFNA5
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| interferon alpha 5 | MIM:147565 | Ensembl:ENSG00000147873 | HGNC:HGNC:5426 | PA29665 | 9p21.3 |
Gene Categories:
DRUGGABLE GENOMEGO terms in IFNA5
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0002250 | adaptive immune response |
| BP | IBA | GO:0002286 | T cell activation involved in immune response |
| BP | IBA | GO:0002323 | natural killer cell activation involved in immune response |
| BP | IBA | GO:0006959 | humoral immune response |
| BP | TAS | GO:0007596 | blood coagulation |
| BP | IEA | GO:0010469 | regulation of signaling receptor activity |
| BP | IBA | GO:0019221 | cytokine-mediated signaling pathway |
| BP | IBA | GO:0030183 | B cell differentiation |
| BP | IBA | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein |
| BP | IBA | GO:0042100 | B cell proliferation |
| BP | IBA | GO:0043330 | response to exogenous dsRNA |
| BP | IEA | GO:0051607 | defense response to virus |
| BP | TAS | GO:0060337 | type I interferon signaling pathway |
| CC | TAS | GO:0005576 | extracellular region |
| CC | IBA | GO:0005615 | extracellular space |
| MF | IBA | GO:0005125 | cytokine activity |
| MF | TAS | GO:0005126 | cytokine receptor binding |
| MF | IBA | GO:0005132 | type I interferon receptor binding |
Gene expression in normal tissue: IFNA5
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in IFNA5
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-109582 | Hemostasis |
| reactome | R-HSA-1280215 | Cytokine Signaling in Immune system |
| reactome | R-HSA-1280215 | Cytokine Signaling in Immune system |
| reactome | R-HSA-168249 | Innate Immune System |
| reactome | R-HSA-168256 | Immune System |
| reactome | R-HSA-168256 | Immune System |
| reactome | R-HSA-168928 | DDX58/IFIH1-mediated induction of interferon-alpha/beta |
| reactome | R-HSA-909733 | Interferon alpha/beta signaling |
| reactome | R-HSA-909733 | Interferon alpha/beta signaling |
| reactome | R-HSA-912694 | Regulation of IFNA signaling |
| reactome | R-HSA-912694 | Regulation of IFNA signaling |
| reactome | R-HSA-913531 | Interferon Signaling |
| reactome | R-HSA-913531 | Interferon Signaling |
| reactome | R-HSA-933541 | TRAF6 mediated IRF7 activation |
| reactome | R-HSA-983231 | Factors involved in megakaryocyte development and platelet production |
| wikipathways | WP1449 | Regulation of toll-like receptor signaling pathway |
| wikipathways | WP4172 | PI3K-Akt Signaling Pathway |
| wikipathways | WP75 | Toll-like Receptor Signaling Pathway |
| kegg | hsa04060 | Cytokine-cytokine receptor interaction - Homo sapiens (human) |
| kegg | hsa04151 | PI3K-Akt signaling pathway - Homo sapiens (human) |
| kegg | hsa04217 | Necroptosis - Homo sapiens (human) |
| kegg | hsa04620 | Toll-like receptor signaling pathway - Homo sapiens (human) |
| kegg | hsa04621 | NOD-like receptor signaling pathway - Homo sapiens (human) |
| kegg | hsa04622 | RIG-I-like receptor signaling pathway - Homo sapiens (human) |
| kegg | hsa04623 | Cytosolic DNA-sensing pathway - Homo sapiens (human) |
| kegg | hsa04630 | Jak-STAT signaling pathway - Homo sapiens (human) |
| kegg | hsa04650 | Natural killer cell mediated cytotoxicity - Homo sapiens (human) |
| kegg | hsa05152 | Tuberculosis - Homo sapiens (human) |
| kegg | hsa05160 | Hepatitis C - Homo sapiens (human) |
| kegg | hsa05161 | Hepatitis B - Homo sapiens (human) |
| kegg | hsa05162 | Measles - Homo sapiens (human) |
| kegg | hsa05164 | Influenza A - Homo sapiens (human) |
| kegg | hsa05165 | Human papillomavirus infection - Homo sapiens (human) |
| kegg | hsa05167 | Kaposi,s sarcoma-associated herpesvirus infection - Homo sapiens (human) |
| kegg | hsa05168 | Herpes simplex infection - Homo sapiens (human) |
| kegg | hsa05200 | Pathways in cancer - Homo sapiens (human) |
| kegg | hsa05320 | Autoimmune thyroid disease - Homo sapiens (human) |
| pid | cd8tcrdownstreampathway | Downstream signaling in naïve CD8+ T cells |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in IFNA5
CLASSFICATION
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