MOGAT3


Summary: Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM, Mar 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location

GO terms in MOGAT3


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IEA GO:0006071 glycerol metabolic process
BP IEA GO:0019432 triglyceride biosynthetic process
BP TAS GO:0019432 triglyceride biosynthetic process
CC TAS GO:0005789 endoplasmic reticulum membrane
CC IEA GO:0016021 integral component of membrane
MF TAS GO:0003846 2-acylglycerol O-acyltransferase activity
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Gene expression in normal tissue: MOGAT3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in MOGAT3


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Database
Pathway ID
Pathway Des.
reactome R-HSA-1430728 Metabolism
reactome R-HSA-556833 Metabolism of lipids
reactome R-HSA-75109 Triglyceride biosynthesis
reactome R-HSA-8979227 Triglyceride metabolism
wikipathways WP325 Triacylglyceride Synthesis
kegg hsa00561 Glycerolipid metabolism - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD309 17AAG 1
iGMDRD353 PD0325901 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MOGAT3

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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