SELENOV
Summary: This gene encodes a selenoprotein containing a selenocysteine (Sec) residue, which is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is specifically expressed in the testis. It belongs to the SelWTH family, which possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Apr 2017].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Nameselenoprotein V OMIM IDMIM:607919 Ensembl IDEnsembl:ENSG00000186838 HGNC IDHGNC:HGNC:30399 Map Location19q13.2 | |||||
GO terms in SELENOV
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0010269 | response to selenium ion |
| CC | IBA | GO:0005829 | cytosol |
| MF | IPI | GO:0005515 | protein binding |
Gene expression in normal tissue: SELENOV
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SELENOV
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SELENOV
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
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