DNAJB13
Summary: This gene encodes a member of the heat shock protein 40 co-chaperone family which is produced in large amounts in the testis and is located on the radial spokes of the axoneme in human sperm flagella and other flagellar structures. The encoded protein associates with the sperm annulus, as part of the septin complex, through direct interaction with septin 4, during sperm terminal differentiation. Naturally occurring mutations in this gene are associated with primary ciliary dyskinesia and male infertility. [provided by RefSeq, Apr 2017].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:610263 Ensembl IDEnsembl:ENSG00000187726 HGNC IDHGNC:HGNC:30718 PHARMGKB IDPA142671972 Map Location11q13.4 |
GO terms in DNAJB13
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IPI | GO:0005515 | protein binding |
MF | IBA | GO:0051082 | unfolded protein binding |
MF | IEA | GO:0051082 | unfolded protein binding |
MF | IBA | GO:0051087 | chaperone binding |
CC | IBA | GO:0005829 | cytosol |
CC | IEA | GO:0005930 | axoneme |
Gene expression in normal tissue: DNAJB13
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in DNAJB13
Loading, please wait...
Database | Pathway ID | Pathway Des. |
---|---|---|
No matching records found |
Gene-Drug: Aster Plot
Loading, please wait...
Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD353 | PD0325901 | 1 |
Showing 1 to 1 of 1 rows
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in DNAJB13
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
---|---|---|---|---|---|---|---|---|
No matching records found |