KIF5A

Summary: This gene encodes a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport. Mutations in this gene cause autosomal dominant spastic paraplegia 10. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namekinesin family member 5A
OMIM IDMIM:602821
Ensembl IDEnsembl:ENSG00000155980
HGNC IDHGNC:HGNC:6323
PHARMGKB IDPA30107
Map Location12q13.3

GO terms in KIF5A


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Term Type
Evidence Type
GO Term ID
GO Des.
CC TAS GO:0005829 cytosol
CC IBA GO:0005871 kinesin complex
CC TAS GO:0005871 kinesin complex
CC IBA GO:0005874 microtubule
CC IEA GO:0005874 microtubule
CC HDA GO:0016020 membrane
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Gene expression in normal tissue: KIF5A

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

ERK MAPK signaling1

Pathways in KIF5A


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Database
Pathway ID
Pathway Des.
kegg hsa04144 Endocytosis - Homo sapiens (human)
kegg hsa04728 Dopaminergic synapse - Homo sapiens (human)
reactome R-HSA-109582 Hemostasis
reactome R-HSA-1280218 Adaptive Immune System
reactome R-HSA-162582 Signal Transduction
reactome R-HSA-168256 Immune System
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in KIF5A

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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