TM4SF1
Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| transmembrane 4 L six family member 1 | MIM:191155 | Ensembl:ENSG00000169908 | HGNC:HGNC:11853 | PA36554 | 3q25.1 |
Gene Categories:
DRUGGABLE GENOMEGO terms in TM4SF1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ND | GO:0003674 | molecular_function |
| MF | IPI | GO:0005515 | protein binding |
| BP | ND | GO:0008150 | biological_process |
| CC | IDA | GO:0005887 | integral component of plasma membrane |
| CC | IBA | GO:0016021 | integral component of membrane |
Gene expression in normal tissue: TM4SF1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TM4SF1
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TM4SF1
CLASSFICATION
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