MKI67
Summary: This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:176741 Ensembl IDEnsembl:ENSG00000148773 HGNC IDHGNC:HGNC:7107 PHARMGKB IDPA30825 Map Location10q26.2 | |||||
Gene Categories:
TUMOR SUPPRESSORGO terms in MKI67
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0007049 | cell cycle |
| BP | IDA | GO:0007088 | regulation of mitotic nuclear division |
| BP | ISS | GO:0008283 | cell proliferation |
| BP | TAS | GO:0008283 | cell proliferation |
| BP | IDA | GO:0051983 | regulation of chromosome segregation |
| BP | ISS | GO:1902275 | regulation of chromatin organization |
Gene expression in normal tissue: MKI67
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MKI67
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP2572 | Primary Focal Segmental Glomerulosclerosis FSGS |
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Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD241 | Sunitinib | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MKI67
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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