MTHFD2L

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namemethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like
OMIM IDMIM:614047
Ensembl IDEnsembl:ENSG00000163738
HGNC IDHGNC:HGNC:31865
PHARMGKB IDPA134943916
Map Location4q13.3

GO terms in MTHFD2L


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0004477 methenyltetrahydrofolate cyclohydrolase activity
MF TAS GO:0004477 methenyltetrahydrofolate cyclohydrolase activity
MF IBA GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity
MF TAS GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity
MF IBA GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity
CC IEA GO:0005743 mitochondrial inner membrane
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Gene expression in normal tissue: MTHFD2L

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

Protein stability and degradation1

Pathways in MTHFD2L


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Database
Pathway ID
Pathway Des.
wikipathways WP2525 Trans-sulfuration and one carbon metabolism
kegg hsa00670 One carbon pool by folate - Homo sapiens (human)
humancyc PWY-2201 folate transformations I
reactome R-HSA-1430728 Metabolism
reactome R-HSA-196757 Metabolism of folate and pterines
reactome R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD309 17AAG 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MTHFD2L

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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