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Summary: Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008].

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Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
Namemoesin OMIM IDMIM:309845 Ensembl IDEnsembl:ENSG00000147065 HGNC IDHGNC:HGNC:7373 PHARMGKB IDPA31178 Map LocationXq12

Gene Categories:

CELL SURFACE

GO terms in MSN

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Term Type	Evidence Type	GO Term ID	GO Des.
CC	IEA	GO:0001931	uropod
CC	HDA	GO:0005615	extracellular space
CC	HDA	GO:0005634	nucleus
CC	HDA	GO:0005737	cytoplasm
CC	IDA	GO:0005829	cytosol
CC	TAS	GO:0005829	cytosol

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Gene expression in normal tissue: MSN

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in MSN

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Database	Pathway ID	Pathway Des.
reactome	R-HSA-1266738	Developmental Biology
reactome	R-HSA-1266738	Developmental Biology
reactome	R-HSA-1280215	Cytokine Signaling in Immune system
reactome	R-HSA-168256	Immune System
reactome	R-HSA-373760	L1CAM interactions
reactome	R-HSA-373760	L1CAM interactions

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Gene-Drug: Aster Plot

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Drug ID	Drug Name	Model Num.
iGMDRD144	NSC95397	3
iGMDRD670	ML 210	3
iGMDRD546	BMS-754807	3
iGMDRD779	PRL-3 Inhibitor I	1

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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in MSN

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	Model	Level	Reference ID	Tissue	Cancer	Drug	Clinical Response	Source
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