CNOT3

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
NameCCR4-NOT transcription complex subunit 3
OMIM IDMIM:604910
Ensembl IDEnsembl:ENSG00000088038
HGNC IDHGNC:HGNC:7879
PHARMGKB IDPA26674
Map Location19q13.42

Gene Categories:

TUMOR SUPPRESSOR

GO terms in CNOT3


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Term Type
Evidence Type
GO Term ID
GO Des.
BP TAS GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening
BP IEA GO:0001829 trophectodermal cell differentiation
BP IEA GO:0006351 transcription, DNA-templated
BP IEA GO:0006355 regulation of transcription, DNA-templated
BP TAS GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
BP IBA GO:0017148 negative regulation of translation
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Gene expression in normal tissue: CNOT3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in CNOT3


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Database
Pathway ID
Pathway Des.
kegg hsa03018 RNA degradation - Homo sapiens (human)
reactome R-HSA-212436 Generic Transcription Pathway
reactome R-HSA-3700989 Transcriptional Regulation by TP53
reactome R-HSA-429914 Deadenylation-dependent mRNA decay
reactome R-HSA-429947 Deadenylation of mRNA
reactome R-HSA-6791312 TP53 Regulates Transcription of Cell Cycle Genes
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD589 HG-5-113-01 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CNOT3

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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