CALY
Summary: The protein encoded by this gene is a type II single transmembrane protein. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with D1 dopamine receptor and may interact with other DA receptor subtypes and/or GPCRs. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:604647 Ensembl IDEnsembl:ENSG00000130643 HGNC IDHGNC:HGNC:17938 PHARMGKB IDPA162380987 Map Location10q26.3 | |||||
GO terms in CALY
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0006897 | endocytosis |
| BP | IEA | GO:0007212 | dopamine receptor signaling pathway |
| BP | IBA | GO:0016197 | endosomal transport |
| BP | IMP | GO:0045807 | positive regulation of endocytosis |
| BP | IBA | GO:0048268 | clathrin coat assembly |
| BP | IDA | GO:0048268 | clathrin coat assembly |
Gene expression in normal tissue: CALY
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CALY
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa04728 | Dopaminergic synapse - Homo sapiens (human) |
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Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CALY
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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