EGFL7
Summary: This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:608582 Ensembl IDEnsembl:ENSG00000172889 HGNC IDHGNC:HGNC:20594 PHARMGKB IDPA134928613 Map Location9q34.3 | |||||
GO terms in EGFL7
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0005102 | signaling receptor binding |
| MF | IEA | GO:0005509 | calcium ion binding |
| BP | IEA | GO:0001525 | angiogenesis |
| BP | ISS | GO:0001568 | blood vessel development |
| BP | ISS | GO:0001570 | vasculogenesis |
| BP | IMP | GO:0001938 | positive regulation of endothelial cell proliferation |
Gene expression in normal tissue: EGFL7
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in EGFL7
Loading, please wait...
Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
Loading, please wait...
Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 2 |
Showing 1 to 1 of 1 rows
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in EGFL7
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.