RXFP3
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| relaxin family peptide receptor 3 | MIM:609445 | Ensembl:ENSG00000182631 | HGNC:HGNC:24883 | PA134868535 | 5p13.2 |
GO terms in RXFP3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | TAS | GO:0005886 | plasma membrane |
| CC | IBA | GO:0005887 | integral component of plasma membrane |
| CC | TAS | GO:0005887 | integral component of plasma membrane |
| BP | TAS | GO:0007186 | G-protein coupled receptor signaling pathway |
| BP | IBA | GO:0007188 | adenylate cyclase-modulating G-protein coupled receptor signaling pathway |
| BP | IBA | GO:0007218 | neuropeptide signaling pathway |
| BP | IEA | GO:0007218 | neuropeptide signaling pathway |
| BP | IMP | GO:0032467 | positive regulation of cytokinesis |
| BP | IEA | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway |
| MF | TAS | GO:0004930 | G-protein coupled receptor activity |
| MF | IBA | GO:0004966 | galanin receptor activity |
| MF | IBA | GO:0008528 | G-protein coupled peptide receptor activity |
Gene expression in normal tissue: RXFP3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RXFP3
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa04080 | Neuroactive ligand-receptor interaction - Homo sapiens (human) |
| kegg | hsa04926 | Relaxin signaling pathway - Homo sapiens (human) |
| wikipathways | WP117 | GPCRs, Other |
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-372790 | Signaling by GPCR |
| reactome | R-HSA-373076 | Class A/1 (Rhodopsin-like receptors) |
| reactome | R-HSA-375276 | Peptide ligand-binding receptors |
| reactome | R-HSA-388396 | GPCR downstream signalling |
| reactome | R-HSA-418594 | G alpha (i) signalling events |
| reactome | R-HSA-444821 | Relaxin receptors |
| reactome | R-HSA-500792 | GPCR ligand binding |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RXFP3
CLASSFICATION
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