RXFP3
Summary:
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
relaxin family peptide receptor 3 | MIM:609445 | Ensembl:ENSG00000182631 | HGNC:HGNC:24883 | PA134868535 | 5p13.2 |
GO terms in RXFP3
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | TAS | GO:0005886 | plasma membrane |
CC | IBA | GO:0005887 | integral component of plasma membrane |
CC | TAS | GO:0005887 | integral component of plasma membrane |
BP | TAS | GO:0007186 | G-protein coupled receptor signaling pathway |
BP | IBA | GO:0007188 | adenylate cyclase-modulating G-protein coupled receptor signaling pathway |
BP | IBA | GO:0007218 | neuropeptide signaling pathway |
BP | IEA | GO:0007218 | neuropeptide signaling pathway |
BP | IMP | GO:0032467 | positive regulation of cytokinesis |
BP | IEA | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway |
MF | TAS | GO:0004930 | G-protein coupled receptor activity |
MF | IBA | GO:0004966 | galanin receptor activity |
MF | IBA | GO:0008528 | G-protein coupled peptide receptor activity |
Gene expression in normal tissue: RXFP3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RXFP3
Database | Pathway ID | Pathway Des. |
---|---|---|
kegg | hsa04080 | Neuroactive ligand-receptor interaction - Homo sapiens (human) |
kegg | hsa04926 | Relaxin signaling pathway - Homo sapiens (human) |
wikipathways | WP117 | GPCRs, Other |
reactome | R-HSA-162582 | Signal Transduction |
reactome | R-HSA-372790 | Signaling by GPCR |
reactome | R-HSA-373076 | Class A/1 (Rhodopsin-like receptors) |
reactome | R-HSA-375276 | Peptide ligand-binding receptors |
reactome | R-HSA-388396 | GPCR downstream signalling |
reactome | R-HSA-418594 | G alpha (i) signalling events |
reactome | R-HSA-444821 | Relaxin receptors |
reactome | R-HSA-500792 | GPCR ligand binding |
Gene in drug-gene network: Network Plot
![](image/gene_network_legends.png)
Gene-drug targets distribution
Gene Structure: PDB
Models in RXFP3