FXYD6


Summary: This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes phosphohippolin, which likely affects the activity of Na,K-ATPase. Multiple alternatively spliced transcript variants encoding the same protein have been described. Related pseudogenes have been identified on chromosomes 10 and X. Read-through transcripts have been observed between this locus and the downstream sodium/potassium-transporting ATPase subunit gamma (FXYD2, GeneID 486) locus.[provided by RefSeq, Feb 2011].

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Name
OMIM ID
Ensembl ID
HGNC ID
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Gene Categories:

ION CHANNELTRANSPORTER

GO terms in FXYD6


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IDA GO:0005886 plasma membrane
CC TAS GO:0005886 plasma membrane
BP ND GO:0008150 biological_process
BP IEA GO:0034220 ion transmembrane transport
BP IBA GO:2000649 regulation of sodium ion transmembrane transporter activity
MF ND GO:0003674 molecular_function
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Gene expression in normal tissue: FXYD6

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in FXYD6


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Database
Pathway ID
Pathway Des.
reactome R-HSA-382551 Transport of small molecules
reactome R-HSA-397014 Muscle contraction
reactome R-HSA-5576891 Cardiac conduction
reactome R-HSA-5578775 Ion homeostasis
reactome R-HSA-936837 Ion transport by P-type ATPases
reactome R-HSA-983712 Ion channel transport
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD309 17AAG 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in FXYD6

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Model
Level
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Cancer
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