GDAP1
Summary: This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene. [provided by RefSeq, Feb 2012].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:606598 Ensembl IDEnsembl:ENSG00000104381 HGNC IDHGNC:HGNC:15968 PHARMGKB IDPA28626 Map Location8q21.11 | |||||
GO terms in GDAP1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0000266 | mitochondrial fission |
| BP | IDA | GO:0000266 | mitochondrial fission |
| BP | IBA | GO:0006626 | protein targeting to mitochondrion |
| BP | IMP | GO:0006626 | protein targeting to mitochondrion |
| BP | IBA | GO:0007005 | mitochondrion organization |
| BP | IBA | GO:0008053 | mitochondrial fusion |
Gene expression in normal tissue: GDAP1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in GDAP1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in GDAP1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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