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GDAP1

Summary: This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene. [provided by RefSeq, Feb 2012].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
ganglioside induced differentiation associated protein 1	MIM:606598	Ensembl:ENSG00000104381	HGNC:HGNC:15968	PA28626	8q21.11

GO terms in GDAP1

Term Type	Evidence Type	GO Term ID	GO Des.
BP	IBA	GO:0000266	mitochondrial fission
BP	IDA	GO:0000266	mitochondrial fission
BP	IBA	GO:0006626	protein targeting to mitochondrion
BP	IMP	GO:0006626	protein targeting to mitochondrion
BP	IBA	GO:0007005	mitochondrion organization
BP	IBA	GO:0008053	mitochondrial fusion
BP	IMP	GO:0008053	mitochondrial fusion
BP	IEA	GO:0032526	response to retinoic acid
BP	IEA	GO:0071305	cellular response to vitamin D
CC	HDA	GO:0005634	nucleus
CC	IBA	GO:0005739	mitochondrion
CC	IDA	GO:0005739	mitochondrion
CC	IDA	GO:0005829	cytosol
CC	HDA	GO:0016020	membrane
CC	IBA	GO:0031307	integral component of mitochondrial outer membrane
CC	IDA	GO:0031307	integral component of mitochondrial outer membrane

Gene expression in normal tissue: GDAP1

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Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in GDAP1

Database	Pathway ID	Pathway Des.

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD353	PD0325901	1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in GDAP1

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DATATYPES

CLASSFICATION

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