SASH3
Summary: The protein encoded by this gene contains a Src homology-3 (SH3) domain and a sterile alpha motif (SAM), both of which are found in proteins involved in cell signaling. This protein may function as a signaling adapter protein in lymphocytes.[provided by RefSeq, Sep 2009].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:300441 Ensembl IDEnsembl:ENSG00000122122 HGNC IDHGNC:HGNC:15975 PHARMGKB IDPA162402388 Map LocationXq26.1 | |||||
GO terms in SASH3
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0002639 | positive regulation of immunoglobulin production |
| BP | IEA | GO:0002639 | positive regulation of immunoglobulin production |
| BP | IEA | GO:0002726 | positive regulation of T cell cytokine production |
| BP | IBA | GO:0002821 | positive regulation of adaptive immune response |
| BP | IBA | GO:0009966 | regulation of signal transduction |
| BP | IBA | GO:0030890 | positive regulation of B cell proliferation |
Gene expression in normal tissue: SASH3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SASH3
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SASH3
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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