RHOF
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| ras homolog family member F, filopodia associated | Ensembl:ENSG00000139725 | HGNC:HGNC:15703 | PA24954 | 12q24.31 |
GO terms in RHOF
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0007015 | actin filament organization |
| BP | IDA | GO:0007015 | actin filament organization |
| BP | IBA | GO:0007163 | establishment or maintenance of cell polarity |
| BP | IEA | GO:0007264 | small GTPase mediated signal transduction |
| BP | IBA | GO:0007266 | Rho protein signal transduction |
| BP | IBA | GO:0008360 | regulation of cell shape |
| BP | IBA | GO:0016477 | cell migration |
| BP | IBA | GO:0030334 | regulation of cell migration |
| BP | IBA | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity |
| BP | IBA | GO:0032956 | regulation of actin cytoskeleton organization |
| BP | TAS | GO:0043312 | neutrophil degranulation |
| BP | IBA | GO:0051017 | actin filament bundle assembly |
| BP | TAS | GO:0051056 | regulation of small GTPase mediated signal transduction |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | TAS | GO:0005829 | cytosol |
| CC | NAS | GO:0005856 | cytoskeleton |
| CC | IBA | GO:0005886 | plasma membrane |
| CC | TAS | GO:0005886 | plasma membrane |
| CC | IBA | GO:0005938 | cell cortex |
| CC | TAS | GO:0030667 | secretory granule membrane |
| CC | IBA | GO:0031410 | cytoplasmic vesicle |
| CC | IBA | GO:0032153 | cell division site |
| CC | IBA | GO:0043231 | intracellular membrane-bounded organelle |
| CC | HDA | GO:0070062 | extracellular exosome |
| MF | IBA | GO:0003924 | GTPase activity |
| MF | NAS | GO:0003924 | GTPase activity |
| MF | IBA | GO:0005525 | GTP binding |
| MF | IEA | GO:0005525 | GTP binding |
| MF | IBA | GO:0019901 | protein kinase binding |
Gene expression in normal tissue: RHOF
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RHOF
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-168249 | Innate Immune System |
| reactome | R-HSA-168256 | Immune System |
| reactome | R-HSA-194315 | Signaling by Rho GTPases |
| reactome | R-HSA-194840 | Rho GTPase cycle |
| reactome | R-HSA-6798695 | Neutrophil degranulation |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RHOF
CLASSFICATION
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