PARP16
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| poly(ADP-ribose) polymerase family member 16 | Ensembl:ENSG00000138617 | HGNC:HGNC:26040 | PA134984504 | 15q22.31 |
GO terms in PARP16
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IBA | GO:0005622 | intracellular |
| CC | IBA | GO:0005635 | nuclear envelope |
| CC | IDA | GO:0005635 | nuclear envelope |
| CC | IBA | GO:0005783 | endoplasmic reticulum |
| CC | IMP | GO:0005783 | endoplasmic reticulum |
| CC | IEA | GO:0005789 | endoplasmic reticulum membrane |
| CC | TAS | GO:0005829 | cytosol |
| CC | HDA | GO:0016020 | membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| CC | IBA | GO:0071782 | endoplasmic reticulum tubular network |
| CC | IMP | GO:0071782 | endoplasmic reticulum tubular network |
| BP | IBA | GO:0006471 | protein ADP-ribosylation |
| BP | IMP | GO:0006471 | protein ADP-ribosylation |
| BP | IBA | GO:0030968 | endoplasmic reticulum unfolded protein response |
| BP | IMP | GO:0030968 | endoplasmic reticulum unfolded protein response |
| BP | TAS | GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway |
| BP | IMP | GO:0060548 | negative regulation of cell death |
| BP | IMP | GO:0070213 | protein auto-ADP-ribosylation |
| BP | IMP | GO:0071902 | positive regulation of protein serine/threonine kinase activity |
| BP | IEA | GO:1990830 | cellular response to leukemia inhibitory factor |
| MF | IBA | GO:0003950 | NAD+ ADP-ribosyltransferase activity |
| MF | IMP | GO:0003950 | NAD+ ADP-ribosyltransferase activity |
| MF | TAS | GO:0003950 | NAD+ ADP-ribosyltransferase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IBA | GO:0019900 | kinase binding |
| MF | IPI | GO:0019900 | kinase binding |
| MF | IBA | GO:0043539 | protein serine/threonine kinase activator activity |
| MF | IMP | GO:0043539 | protein serine/threonine kinase activator activity |
Gene expression in normal tissue: PARP16
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PARP16
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1430728 | Metabolism |
| reactome | R-HSA-196807 | Nicotinate metabolism |
| reactome | R-HSA-196849 | Metabolism of water-soluble vitamins and cofactors |
| reactome | R-HSA-196854 | Metabolism of vitamins and cofactors |
| reactome | R-HSA-197264 | Nicotinamide salvaging |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PARP16
CLASSFICATION
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