TUG1
Summary: This gene produces a long non-coding RNA that interacts with the Polycomb repressor complex and functions in the epigenetic regulation of transcription. This RNA promotes cell proliferation and is upregulated in tumor cells. It may act as a sponge for microRNAs. The homologous mouse gene is required for differentiation of retina. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2017].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:614971 Ensembl IDEnsembl:ENSG00000253352 HGNC IDHGNC:HGNC:26066 PHARMGKB IDPA164727367 Map Location22q12.2 | |||||
GO terms in TUG1
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0042478 | regulation of eye photoreceptor cell development |
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Gene expression in normal tissue: TUG1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TUG1
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD353 | PD0325901 | 1 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TUG1
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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