TMCO3
Summary: This gene encodes a member of the monovalent cation:proton antiporter 2 (CPA2) family of transporter proteins. Members of this family typically couple the export of monovalent cations, such as potassium or sodium, to the import of protons across cellular membranes. Mutations in this gene have been identified in patients with a rare inherited vision defect, cornea guttata with anterior polar cataract. [provided by RefSeq, Mar 2017].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
OMIM IDMIM:617134 Ensembl IDEnsembl:ENSG00000150403 HGNC IDHGNC:HGNC:20329 PHARMGKB IDPA134989495 Map Location13q34 |
GO terms in TMCO3
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Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
MF | IEA | GO:0015299 | solute:proton antiporter activity |
BP | IEA | GO:1902600 | proton transmembrane transport |
CC | IEA | GO:0016021 | integral component of membrane |
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Gene expression in normal tissue: TMCO3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TMCO3
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Database | Pathway ID | Pathway Des. |
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No matching records found |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
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iGMDRD68 | Paclitaxel | 1 |
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in TMCO3
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
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No matching records found |