ENOX1


Summary: The protein encoded by this gene is involved in plasma membrane electron transport pathways. The encoded protein has both a hydroquinone (NADH) oxidase activity and a protein disulfide-thiol interchange activity. The two activities cycle with a periodicity of 24 minutes, with one activity being at its peak when the other is at its lowest. [provided by RefSeq, Dec 2016].

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OMIM ID
Ensembl ID
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Gene Categories:

DRUGGABLE GENOME

GO terms in ENOX1


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IEA GO:0005615 extracellular space
CC IDA GO:0005886 plasma membrane
CC IEA GO:0009897 external side of plasma membrane
BP IEA GO:0007624 ultradian rhythm
BP IEA GO:0055114 oxidation-reduction process
MF IEA GO:0003676 nucleic acid binding
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Gene expression in normal tissue: ENOX1

16 tissues mixtureadiposeadrenalbrainbreastcolonheartkidneyliverlunglymph nodeovaryprostateskeletal muscletestesthyroidwhite blood cells

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Gene-drug pathway distribution

ERK MAPK signaling1

Pathways in ENOX1


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 1
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Gene in drug-gene network: Network Plot

KRASKRASZNF273ZNF273PAX5PAX5CCDC117CCDC117SLC16A3SLC16A3NPAS2NPAS2RXRARXRAZFP36L2ZFP36L2RNU2-11PRNU2-11PAPOC1APOC1TCF7L2TCF7L2ZNF682ZNF682BRAFBRAFWDR24WDR24FERMT1FERMT1NHLRC1NHLRC1ZNF736ZNF736RN7SL477PRN7SL477PNRASNRASKLHL32KLHL32PD0325901PD0325901ENOX1ENOX1

Gene-drug targets distribution

Gene Structure: PDB

Models in ENOX1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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