ENOX1
Summary: The protein encoded by this gene is involved in plasma membrane electron transport pathways. The encoded protein has both a hydroquinone (NADH) oxidase activity and a protein disulfide-thiol interchange activity. The two activities cycle with a periodicity of 24 minutes, with one activity being at its peak when the other is at its lowest. [provided by RefSeq, Dec 2016].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| ecto-NOX disulfide-thiol exchanger 1 | MIM:610914 | Ensembl:ENSG00000120658 | HGNC:HGNC:25474 | PA162385069 | 13q14.11 |
Gene Categories:
DRUGGABLE GENOMEGO terms in ENOX1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IEA | GO:0005615 | extracellular space |
| CC | IDA | GO:0005886 | plasma membrane |
| CC | IEA | GO:0009897 | external side of plasma membrane |
| BP | IEA | GO:0007624 | ultradian rhythm |
| BP | IEA | GO:0055114 | oxidation-reduction process |
| MF | IEA | GO:0003676 | nucleic acid binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0016491 | oxidoreductase activity |
Gene expression in normal tissue: ENOX1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ENOX1
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ENOX1
CLASSFICATION
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