ATG2B

Summary: This gene encodes a protein required for autophagy. The encoded protein is involved in autophagosome formation. A germline duplication of a region that includes this gene is associated with predisposition to myeloid malignancies. [provided by RefSeq, Jul 2016].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameautophagy related 2B
OMIM IDMIM:616226
Ensembl IDEnsembl:ENSG00000066739
HGNC IDHGNC:HGNC:20187
PHARMGKB IDPA162377102
Map Location14q32.2

GO terms in ATG2B


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IBA GO:0000407 phagophore assembly site
CC IDA GO:0005654 nucleoplasm
CC IEA GO:0005811 lipid droplet
CC IBA GO:0019898 extrinsic component of membrane
CC IEA GO:0034045 phagophore assembly site membrane
BP IBA GO:0000045 autophagosome assembly
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Gene expression in normal tissue: ATG2B

Gene-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Gene-drug pathway distribution

ERK MAPK signaling1

Pathways in ATG2B


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Database
Pathway ID
Pathway Des.
kegg hsa04136 Autophagy - other - Homo sapiens (human)
kegg hsa04140 Autophagy - animal - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD353 PD0325901 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ATG2B

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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