ATG2B


Summary: This gene encodes a protein required for autophagy. The encoded protein is involved in autophagosome formation. A germline duplication of a region that includes this gene is associated with predisposition to myeloid malignancies. [provided by RefSeq, Jul 2016].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
autophagy related 2BMIM:616226Ensembl:ENSG00000066739HGNC:HGNC:20187PA16237710214q32.2

GO terms in ATG2B


Term TypeEvidence TypeGO Term IDGO Des.
CCIBAGO:0000407phagophore assembly site
CCIDAGO:0005654nucleoplasm
CCIEAGO:0005811lipid droplet
CCIBAGO:0019898extrinsic component of membrane
CCIEAGO:0034045phagophore assembly site membrane
BPIBAGO:0000045autophagosome assembly
BPIBAGO:0000422autophagy of mitochondrion
BPIBAGO:0044804autophagy of nucleus

Gene expression in normal tissue: ATG2B

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ATG2B


DatabasePathway IDPathway Des.
kegghsa04136Autophagy - other - Homo sapiens (human)
kegghsa04140Autophagy - animal - Homo sapiens (human)

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259012

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ATG2B

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