| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | IEA | GO:0005737 | cytoplasm |
| CC | IEA | GO:0016605 | PML body |
| CC | IDA | GO:0035861 | site of double-strand break |
| CC | IDA | GO:0090734 | site of DNA damage |
| BP | IDA | GO:0000724 | double-strand break repair via homologous recombination |
| BP | IDA | GO:0006974 | cellular response to DNA damage stimulus |
| BP | IDA | GO:0010212 | response to ionizing radiation |
| BP | IDA | GO:0016567 | protein ubiquitination |
| BP | IEA | GO:0016567 | protein ubiquitination |
| BP | IDA | GO:0031297 | replication fork processing |
| BP | IMP | GO:0031571 | mitotic G1 DNA damage checkpoint |
| BP | IMP | GO:0036297 | interstrand cross-link repair |
| BP | IMP | GO:2000001 | regulation of DNA damage checkpoint |
| MF | IPI | GO:0002039 | p53 binding |
| MF | IDA | GO:0004842 | ubiquitin-protein transferase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0046872 | metal ion binding |
| MF | IPI | GO:0097371 | MDM2/MDM4 family protein binding |