SLC22A15
Summary: Organic ion transporters, such as SLC22A15, transport various medically and physiologically important compounds, including pharmaceuticals, toxins, hormones, neurotransmitters, and cellular metabolites. These transporters are also referred to as amphiphilic solute facilitators (ASFs).[supplied by OMIM, Apr 2004].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| solute carrier family 22 member 15 | MIM:608275 | Ensembl:ENSG00000163393 | HGNC:HGNC:20301 | PA134870374 | 1p13.1 |
GO terms in SLC22A15
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0015711 | organic anion transport |
| BP | IEA | GO:0055085 | transmembrane transport |
Gene expression in normal tissue: SLC22A15
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SLC22A15
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-382551 | Transport of small molecules |
| reactome | R-HSA-425366 | Transport of bile salts and organic acids, metal ions and amine compounds |
| reactome | R-HSA-425407 | SLC-mediated transmembrane transport |
| reactome | R-HSA-549127 | Organic cation transport |
| reactome | R-HSA-549132 | Organic cation/anion/zwitterion transport |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD57 | Chloropentafluorobenzene | 3 |
| iGMDRD499 | PDMP | 3 |
| iGMDRD82 | Quiflapon | 3 |
| iGMDRD132 | (-)-gallocatechin-3-O-gallate | 3 |
| iGMDRD524 | ISX-9 | 3 |
| iGMDRD177 | Teniposide | 1 |
| iGMDRD772 | BRD4770 | 3 |
| iGMDRD202 | Curcumin | 3 |
| iGMDRD307 | Manumycin A | 3 |
| iGMDRD318 | PAC-1 | 3 |
| iGMDRD415 | LE-135 | 3 |
| iGMDRD79 | Gemcitabine | 6 |
| iGMDRD221 | Tamoxifen | 3 |
| iGMDRD532 | Olaparib | 3 |
| iGMDRD144 | NSC95397 | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SLC22A15
CLASSFICATION
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