YEATS2
Summary: Summary: The protein encoded by this gene is a scaffolding subunit of the ATAC complex, which is a complex with acetyltransferase activity on histones H3 and H4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2017].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| YEATS domain containing 2 | MIM:613373 | Ensembl:ENSG00000163872 | HGNC:HGNC:25489 | PA134922615 | 3q27.1 |
GO terms in YEATS2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ISM | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | IPI | GO:0017025 | TBP-class protein binding |
| MF | IDA | GO:0042393 | histone binding |
| MF | IDA | GO:0140030 | modification-dependent protein binding |
| CC | IDA | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex |
| CC | IEA | GO:0072686 | mitotic spindle |
| BP | IDA | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| BP | IDA | GO:0043966 | histone H3 acetylation |
| BP | IDA | GO:0045892 | negative regulation of transcription, DNA-templated |
Gene expression in normal tissue: YEATS2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in YEATS2
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-3214847 | HATs acetylate histones |
| reactome | R-HSA-3247509 | Chromatin modifying enzymes |
| reactome | R-HSA-4839726 | Chromatin organization |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in YEATS2
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.